Substantive comments add to the discussion and provide your fellow students with

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Substantive comments add to the discussion and provide your fellow students with

Substantive comments add to the discussion and provide your fellow students with information that will enhance the learning environment.
References and citations should conform to the APA standards.
Remember: Please respect the opinions of others, even if their views differ. In other words, disagree professionally and respectfully.
Plagiarism is never acceptable – give credit when credit is due – cite your sources.
DOI reference link
Responses need to address all components of the question, demonstrate critical thinking and analysis, and include peer reviewed journal evidence to support the student’s position.
PLEASE RESPOND TO THE FOLLOWING POST:
Consider your topic of interest and the purpose for exploring this topic.
topic of interest was finding research validating the effectiveness of exercise to reduce symptoms of depression.  The topic was of interest to me for the following reasons:.  Family history of depression on the paternal male side with completed suicide of my brother, 1st cousin and grandfather. In addition, throughout my profession, I have observed side effects to various antidepressant medications, abuse of antidepressant medications by mixing with other substances, and non-adherence to medications as catalysts to worsen depressive symptoms.
What outcomes would you like to see emerge from this?
Some individuals do not enjoy exercising, furthermore, individual response to exercise can vary with different exercise modalities. The desired outcomes would be for further research to validate the effectiveness of RewP testing.  Further research on the effects of acute and chronic exercise on brain function by measuring event related potential (ERP)  would also be helpful in validating positive effects of exercise. ERP’s are small electrical potentials from the cortex of the brain, they can provide information about brain activity such as higher level processing (thinking) and sensory perception processes such as learning, memory, emotions and expectations.(Gusatovic et al., 2022). Further evidence supporting the validity of the RewP as a predictive measurement tool supporting the positive effects of exercise, may lead to more providers utilizing the equipment, thus hoping the cost of testing would decrease. If more providers were able to use the RewP as a measurement to predict positive response, they would be able to customize the right modality of exercise to obtain maximum results.
How would you measure these outcomes?
I would utilize tools like those used by (Brush et al., 2020).  EEG-flankers and ERP measurements for RewP measurements.  Reward positivity, (RewP) is a measure thought to be correlated with the positive reward processing center of the brain. The results of the study suggested a greater (RewP) predicts a response to exercise for adults with major depression (Brush et al., 2020).   In addition, I would use self-assessment tools and questionnaires, such as the Mini International Neuropsychiatric Interview, to obtain subjective data pre and post exercise.
Include in your discussion an analysis of how Aiken measured her selected outcomes.
Patient mortality, patient surveys, care quality, patient safety, and nurse reported outcomes such as burnout and job satisfaction were the outcomes measured. Representative samples were gathered from hospitals over 6 countries. Patient mortality data was pulled from 188 hospitals, nurse reported data was pulled from 243 hospitals and patient ratings were pulled from 182 hospitals (Aiken et al.,2016).  An analysis was performed on the data pertaining to outcomes such as patient discharge, adverse events, hospital characteristics, as well as feedback from patients and nurses (Aiken et al.,2016).  
References:
Aiken, L., Sloane, D., Griffiths, P., Rafferty, A. Bruyneel, L., McHugh, M., Maier, C., Casbas, T., Ball., J., Ausserhofer, D.,  Sermeus, W., (2016). Nursing skill mix in European hospitals: cross-sectional study of the association with mortality, patient ratings, and quality of care. BMJ Quality and Safety 26. doi: 10.1136/bmjqs-2016-006197
Brush, C. J., Hajcak, G., Bocchine, A. J., Ude, A. A., Muniz, K. M., Foti, D., & Alderman, B. L. (2020). A randomized trial of aerobic exercise for major depression: Examining neural indicators of reward and cognitive control as predictors and treatment targets. Psychological Medicine, 52(5), 893–903. https://doi.org/10.1017/s0033291720002573Links to an external site.
Gusatovic, J., Mathias, H. G., Hasselbalch, S. G., & Kristian, S. F. (2022). Effects of aerobic exercise on event-related potentials related to cognitive performance: a systematic review. PeerJ, https://doi.org/10.7717/peerj.13604Links to an external site.  DOI:10.7717/peerj.13604

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